ALTER TABLE ... MODIFY TTL

ALTER TABLE [db.]table_name [ON CLUSTER cluster] MODIFY TTL ttl_expression;

ALTER TABLE [db.]table_name [ON CLUSTER cluster] REMOVE TTL

CREATE TABLE table_with_ttl
(
    event_time DateTime,
    UserID UInt64,
    Comment String
)
ENGINE MergeTree()
ORDER BY tuple()
TTL event_time + INTERVAL 3 MONTH
SETTINGS min_bytes_for_wide_part = 0;

INSERT INTO table_with_ttl VALUES (now(), 1, 'username1');

INSERT INTO table_with_ttl VALUES (now() - INTERVAL 4 MONTH, 2, 'username2');

OPTIMIZE TABLE table_with_ttl FINAL;
SELECT * FROM table_with_ttl FORMAT PrettyCompact;

┌─────────event_time────┬──UserID─┬─────Comment──┐
│   2020-12-11 12:44:57 │       1 │    username1 │
└───────────────────────┴─────────┴──────────────┘

ALTER TABLE table_with_ttl REMOVE TTL;

INSERT INTO table_with_ttl VALUES (now() - INTERVAL 4 MONTH, 2, 'username2');
OPTIMIZE TABLE table_with_ttl FINAL;
SELECT * FROM table_with_ttl FORMAT PrettyCompact;

┌─────────event_time────┬──UserID─┬─────Comment──┐
│   2020-12-11 12:44:57 │       1 │    username1 │
│   2020-08-11 12:44:57 │       2 │    username2 │
└───────────────────────┴─────────┴──────────────┘